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Your global leading partner in science for end to end CRDMO services

Toxicology Studies

Jubilant Biosys offers a large array of GLP and non-GLP preclinical toxicology studies to its customers. The studies, in which our toxicology services team has expertise (certified toxicologist by American Board of Toxicology, DABT and pathologist by Indian Board of Toxicologic Pathology, DIBTP), comprise of acute, sub-acute, sub-chronic studies in various test systems with different routes of administration, along with in-vitro/in-vivo genotoxicity studies. These studies are performed in compliance with global regulatory guidelines, ICH, OECD, etc. at Jubilant’s GLP certified toxicology lab in India.

Toxicology services

Toxicology Services

We provide a comprehensive range of toxicology and safety pharmacology services in accordance with the international regulatory guidelines. With routine screening of compounds in the R&D phase, we assist in toxicological safety assessment to identify and eliminate the unsafe elements at the earliest stage in drug development.

Jubilant Biosys has the latest facilities to evaluate the candidate compounds in a professional manner that results in the timely delivery of the reports. The rich experience of our scientific team helps our customers meet their specific preclinical and other early-stage product development needs, enhance their decision-making process, and save their time and resources.

Acute Studies

  • Single dose toxicology studies in rodents (rats/mice)
  • Single dose toxicology studies in non-rodents (rabbits)

Repeated Dose Toxicity Studies in Rodents (rats/mice/guinea pigs) and Non-Rodents (rabbits)

  • Sub-acute Toxicity: 14 days DRF and 28 days with toxicokinetic studies (OECD 407)
  • Sub-chronic Toxicity: 90 days with toxicokinetic studies (OECD 408)
  • Standalone Toxicokinetic studies (OECD 417)

Safety Pharmacology (CNS) In-vivo

  • Modified Irwin test (FOB) in rats/mice

Different Routes of Administration

  • Oral through gavage
  • Dermal
  • Subcutaneous
  • Intra-peritoneal
  • Intramuscular
  • Intravenous

Genetic Toxicology Study Services

In-vitro Toxicology Services

  • Bacterial Reverse Mutation Test (Ames Test) using Salmonella Typhimurium and E.coli WP2 uvrA
  • In-vitro Mammalian Chromosome Aberration Test using Human Peripheral Blood Lymphocytes
  • In-vitro micronucleus test using Human Peripheral Blood Lymphocytes

In-vivo Toxicology Services

  • In-vivo Mammalian Erythrocyte Micronucleus Test in Mice/Rat (with and without Toxicokinetic)
  • In-vivo Mammalian Bone Marrow Chromosome Aberration Test in Mice/Rat (with and without Toxicokinetic)

Pathology Services

We offer Stand Alone Pathology Services (tissue processing through slide evaluation and reporting) for the in-life phase of toxicology and efficacy studies conducted elsewhere.