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Delivering the Added Dimension in Drug Discovery Services
In-vitro Biology & Pharmacology Solutions
The In-vitro Biology Group at Jubilant has the infrastructure and expertise to perform a variety of biochemical and cellular assays against most target classes, including enzymes, GPCR’s, NHR’s and transporters.
The department is equipped with state-of-the-art facilities for in-vitro pharmacology services to enable these assays, including sophisticated liquid-handling, compound-handling and assay-detection systems. With a high ratio of PhD scientists, the group of in-vitro pharmacology has the necessary expertise to take on target validation and mechanism studies.
The following functional services are provided:
Biochemical and cell-based assay development and validation
State-of-the-art instrumentation for screening
Fully automated compound management system
Statistical support with IT-enabled screening tools
Advanced algorithms for data processing and quality evaluation
Biology Assay Development & Validation
We offer extensive assay development and validation service at every stage in the discovery and development of pharmaceutical products to evaluate pharmacokinetic parameters, toxicity, safety and efficacy. Our biologists assist you with precise and adaptable cellular assays to meet your preclinical or clinical biomarker sample analysis needs.
Biochemical and Cell-based Assays
Radioactive Binding Assays
Filter Binding Assays
Scintillation Proximity Assays
Calcium dye-based FLIPR Assays
hERG Binding Assays
Whole Blood Assays
Cell Viability (LDH, MTT, Alamar Blue)
Flow Cytometry Assays
Western Blotting and In Cell ELISA
Target or Pathway Specific Assay
DiscoverX Platform, including Beta-arrest in Assays (PathHunter and PathFinder Assays)
Radiometric- SPA, Filter Binding, Flash Plate
Fluorescent- FP, FRET, HTRF, TRF, DELFIA, Lance
Luminescent Alpha Screen
Luminescent Aequorin Assays
Meso Scale Discovery Platform.
Our experienced team of in-vitro pharmacology brings strong problem-solving skills and expertise in a large variety of assays and techniques mentioned above.
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