Jubilant Biosys

Delivering the Added Dimension in Drug Discovery Services

In-vitro Biology & Pharmacology Solutions

The In-vitro Biology Group at Jubilant has the infrastructure and expertise to perform a variety of biochemical and cellular assays against most target classes, including enzymes, GPCR’s, NHR’s and transporters.

The department is equipped with state-of-the-art facilities for in-vitro pharmacology services to enable these assays, including sophisticated liquid-handling, compound-handling and assay-detection systems. With a high ratio of PhD scientists, the group of in-vitro pharmacology has the necessary expertise to take on target validation and mechanism studies.

The following functional services are provided:

  • Biochemical and cell-based assay development and validation
  • State-of-the-art instrumentation for screening
  • Fully automated compound management system
  • Statistical support with IT-enabled screening tools
  • Advanced algorithms for data processing and quality evaluation

Biology Assay Development & Validation

Biochemical and Cell-based Assays

  • Radioactive Binding Assays
  • FRET
  • HTRF
  • Kinetic Assays
  • Filter Binding Assays
  • Scintillation Proximity Assays
  • Calcium dye-based FLIPR Assays
  • hERG Binding Assays
  • Whole Blood Assays
  • Cell Viability (LDH, MTT, Alamar Blue)
  • Flow Cytometry Assays
  • Western Blotting and In Cell ELISA

Target or Pathway Specific Assay

  • DiscoverX Platform, including Beta-arrest in Assays (PathHunter and PathFinder Assays)

Phenotypic Screens

Assay Technologies

  • Radiometric- SPA, Filter Binding, Flash Plate
  • Fluorescent- FP, FRET, HTRF, TRF, DELFIA, Lance
  • Luminescent Alpha Screen
  • Luminescent Aequorin Assays
  • Meso Scale Discovery Platform.

Our experienced team of in-vitro pharmacology brings strong problem-solving skills and expertise in a large variety of assays and techniques mentioned above.