Therapeutic Antibody Database (TAD)

Jubilants initiative to create a database on "Therapeutic Antibodies" aims to capture information on all those antibodies that have been successfully taken from bench to bedside as well as those in various stages of this process providing a window to understand the process involved.

This database would provide in a nutshell the following:

• Information on target molecule

• Antibody construction details

• Clinical trial data

• Dosage regimen and patient profile

• Toxicity data

• Altered cellular and molecular processes

• Animal models used to study the antibody efficacy

• Mode of action of the antibody from a pathway perspective

 Granular mode of data capture makes the database extensively queriable.

Coverage of this exhaustive set allows the users to connect the structural data to specificity and toxicity and in-turn enable hypothesis driven engineering efforts