PathArtTM
    MolSignTM
    Small Molecule Databases
    Nitrilase and Nitrile Hydratase
Knowledgebase
    Register for Demo
       
       
       
       
       
       
       
       

     
Kinase ChemBioBase Database  |  Protease Database  |  GPCR Database  | 
 		 Ion Channel Database  |  Nuclear Receptor Database

    
JUBILANT'S THEMATIC SUITE OF DATABASES

Jubilant has created a niche for itself in the area of discovery informatics and has built highly comprehensive small-molecule databases on targets, to include, Kinase, GPCR, Protease, Ion Channels and Nuclear Receptors. These databases provide information on the chemical and their associated biological activity. Researchers can benefit by using these databases in a specific domain and ease the process of virtual screening.
 
Jubilant has built these databases from scientific and patent literature. The focus on these thematic databases strives to address the complex needs of chemists, modelers and informaticians worldwide, in their quest for discovery of compounds to treat mankind.

      

Technical specifications:
The database can be queried across text, structure and substructure with the built-in query modules.

The database is available in the popular formats (Oracle, SD format, RD format and ISIS/Base ® DB formats)

Data can be exported into multiple formats like Excel.

Applications:
The database would be an invaluable tool in the process of lead identification and prioritization :

Enhances the ability to generate a better set of molecules from chemical libraries for High Throughput Screening , which will improve the probability of success and the productivity of the drug discovery process in a short span of time and thereby reduces the cost of production

Predict properties of new compounds of interest (properties related to level of bio – activity, target specificity, etc.)
Generation of combinatorial library and diversity oriented synthesis for the discovery of novel bioactive compounds
Probabilistic prediction of bioactivity using structural descriptor
Similarity-based methods for the virtual screening of databases
Analyze Quantitative Structure Activity Relationships for use in rational drug design
Compare leads generated against other similar molecules that have been patented
Make available the repository of all published/patented information to discovery scientists

Jubilant is also involved in creating customized curation databases containing relevant information on the targets or leads of interest to discovery scientists. Jubilant Biosys is the leader in creating such high-quality customized databases based on specific client requirement.