Proteases ChemBioBase ™ and protease inhibitors play important roles in ontogeny, differentiation, signal transduction, viral and bacterial infection and host defensive system and also in pathogenicity of various human diseases. Based on the significance of proteases and protease inhibitors in the pathophysiology of several diseases, our database with diverse biological activity information on various protease inhibitors would pave the way for cutting edge technology in drug discovery.
Product Profile:
Jubilant Biosys is building a comprehensive database on small molecule protease inhibitors.
Serine proteases (S1, S3, S35, S58 family), Threonine proteases (T1, T2, T3 family), Cysteine proteases (C1, C2, C50, C63 family), Aspartyl proteases (A1, A2, A6 family), Metalloproteases (M1, M2, M41, M67 family), Proteases of unknown catalytic mechanism (U4, U6, U64 family)
Salient Features
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Enzyme assays (Invitro & Invivo), PK assays |
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Target |
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Mechanism of action |
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Target classification |
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Therapeutic indication |
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Structural information |
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Type (IC50, Ki, %INH, ED50, EC50, LD50, %F, t1/2, CL, Cmax, Vdss etc.,) |
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