Nuclear Receptors are ligand-activated transcription factors. 48 Nuclear Receptors have been identified in human genome. Many of these nuclear receptors are classified as orphan receptors but identification of endogenous substrates is currently of great interest.

Product Profile:

Jubilant Biosys is building a comprehensive small molecule ligand centric database on NUCLEAR HORMONE RECEPTOR. The database is the integrated chemical and biological information of known NHR from Patents and Journals.

	Intended to cover over 85,000 ligands
	Informations would be captured from the estimated 120 scientific journals and 1200 patents.
	Covers 2 8-30 Nuclear Receptors
	The current size of the database is around 29000 records

The NHR ligand centric database integrates structure and bioactivity data in a user-friendly format. Some of the key parameters on which the information is provided are:

	General
	Receptor Assays

General form – Key parameters

	2D chemical structure
	IUPAC name
	Mechanism of action
	Target classification
	Therapeutic indication
	Structural information
	Critical Motifs
	Bibliographic reference

Receptor Assays (Invitro, Transactivation, Cell line & Invivo)– Key parameters

	Bioassay
	Target
	Source (Dose and Unit_D for PK Assays)
	Type
	Value status
	Value
	Unit