G Protein-Coupled Receptor (GPCR) family emerged as prominent drug targets within pharmaceutical research, since approximately 60% of marketed prescription drugs act by selectively addressing representatives of that class of transmembrane signal transduction systems. It is noteworthy that the majority of GPCR-targeted drugs elicit their biological activity by selective agonism or antagonism of biogenic monoamine receptors, while the development status of peptide-binding GPCR-addressing compounds is still in its infancy.

Product Profile

Jubilant Biosys is building a comprehensive small molecule ligand centric database on GPCR agonists/antagonists. The database is the integrated chemical and biological information of known GPCR agonists and antagonists from Patents and Journal articles.

	Estimated to contain over 500,000 ligands
	Information captured from the estimated 3 000 scientific journal articles and 7 000 patents.
	Covers 200 GPCR Targets, which includes 3 classes (A,B,C)

The GPCR ligand centric database integrates structure and bioactivity data in a user-friendly format. Some of the key parameters on which information provided are:

	Chemical Structure
	Molecular weight
	Molecular Formula
	IUPAC Name
	Bioassay, Bioactivity
	Therapeutic Indication
	Target Classification
	Bibliographic Information
	Equivalent Patent Information