JBL performs pharmacokinetic studies for projects at different stages of drug discovery program. JBL scientists are well skilled in designing, performing, and interpreting the results of pharmacokinetic studies. Study design and selection of models are tailored to meet specific project needs. Pharmacokinetic study samples may include blood, bile, cerebrospinal fluid or other matrices, as well as tissue specimens that have special bioanalytical requirements. JBL can also provide pharmacokinetic parameter estimation output, and reports may include a detail interpretation of the data, if required.
Using industry-standard Watson and WinNonlin software JBL can provide following services:
Services
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Non-compartmental pharmacokinetics
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Compartmental pharmacokinetics / simulations.
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Ascending dose (assessment of dose proportionality).
- Repeat dose (assessment of
multiple dose linearity).
- Bioavailability.
- PK/PD modeling.
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