Discovery Services
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 Physicochemical Screening
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In vivo PK/ ADME Screening

JBL offers in vivo pharmacokinetic and ADME studies at various stages of drug discovery program. Scientists at JBL can design and interpret the drug metabolism components, which include the evaluation of various dose regimens and administration routes in rodents with numerous surgical models.

 
            Services          Surgical Models
       
 
  • Bioavailability.
  • Tissue distribution.
  • Dose ranging.
  • Linearity.
  • Proportionality.
  • Biliary excretion.
  • Single, multiple, and cassette dosing.
  • Metabolite profiling
 
  • Bile duct cannulation.
  • Intestinal cannulation.
  • Portal vein cannulation.
  • Jugalar vein cannulation.


 



 
 
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