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ChemBioBaseTM
Jubilant's ChemBioBaseTM is a comprehensive set
of target centric ligand databases. Each of
these databases contains small molecules that
exhibit activity against targets in a particular
family. The ChemBioBaseTM products integrate
assay data and target information with chemical
structure data collected from published patents
and articles, and are provided to users in a
user-friendly format.
Currently available databases are:
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Kinase ChemBioBaseTM - Over 319,000 small
molecules against kinase targets
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GPCR ChemBioBaseTM - Over 400,000 small
molecules comprising agonists, antagonists and
other ligands against GPCR targets
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Nuclear Hormone Receptor ChemBioBaseTM - Over
150,000 agonists, antagonists and other small
molecules against nuclear hormone receptors
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Ion Channel ChemBioBaseTM- Over 100,000 small
molecules against ion channels
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Protease ChemBioBaseTM - Over 400,000 ligands
for proteases
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Phosphodiesterase ChemBioBaseTM - Small
molecules that bind to phosphodiesterase
targets.
Jubilant's ChemBioBaseTM suite allows effective
mining of the chemistry space for ligands
against specific targets of interest in some of
the following ways:
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SAR points allow building of QSAR training
sets
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Develop pharmacophore models
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Prioritize synthesis
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Explore the patent space to discover
opportunities for new drugs Our databases are
invaluable tools in considerably speeding up
the hit-to-lead process.
Technical specifications:
The databases are available in multiple formats
like ISIS/BASE (Flat/ Hierarchical), ISIS/HOST,
Oracle, SD file, RD file, XML.
Key Features:
The ChemBioBaseTM products integrate textual
data on assays and bioactivity with chemical
structure data in a user-friendly format. Some
of the key parameters are:
Versatile searches can be performed using
various combinations of text and structure
fields.
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